Platelet-Rich Fibrin


Platelet-Rich Fibrin (PRF) is a cutting-edge regenerative treatment that harnesses the body's own healing abilities to rejuvenate tissue, accelerate healing, and improve skin health. Often used in medical and aesthetic procedures, PRF offers a natural and effective approach to skin revitalization, hair restoration, and scar healing.

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What is Platelet-Rich Fibrin ?

In aesthetic treatments, PRF works by stimulating the skin’s natural collagen production, enhancing texture, tightening skin, and improving overall skin tone. Derived from your own blood, PRF contains concentrated growth factors, cytokines, and other bioactive molecules that promote tissue regeneration. This minimally invasive procedure can address a variety of concerns such as fine lines, wrinkles, acne scars, and hair thinning, offering long-lasting results with minimal downtime.

  • How PRP Works

    1. Blood Collection and Centrifugation:

    A small blood sample is drawn, which is then processed in a centrifuge. This step separates the blood into different components, concentrating platelets and fibrin into a gel-like substance known as PRF. This gel is rich in growth factors that stimulate healing and tissue regeneration.

    2. Application of PRF:

    The PRF gel is applied to the treatment area, either through injection or topical application. In most cases, it’s used in combination with microneedling, which creates tiny micro-injuries in the skin to help the PRF penetrate deeper into the dermis, boosting its effectiveness.

    3. Collagen Stimulation:

    The growth factors in PRF stimulate fibroblast activity, leading to the production of collagen and elastin. This results in smoother, firmer, and more youthful skin, as collagen is essential for maintaining skin structure and elasticity.

    4. Tissue Regeneration:

    PRF’s cytokines and bioactive molecules also help regenerate damaged skin tissue, improving skin health and texture, reducing signs of aging, and promoting a more even skin tone. The treatment can also help reduce acne scars and improve skin vitality.


  • Common Cosmetic Applications of PRF

    1. Facial Rejuvenation:

    • Fine Lines & Wrinkles: PRF boosts collagen production, reducing fine lines and wrinkles around the eyes, mouth, and forehead.

    • Skin Firmness & Tightening: By enhancing collagen and elastin levels, PRF tightens sagging skin, especially in areas like the jawline, cheeks, and neck.

    • Improved Skin Texture & Tone: PRF accelerates cell turnover, which helps smooth out rough patches, brighten skin, and even out skin tone.


    2. PRF is suitable for most skin types and those looking to address pigmentation concerns like:

    • Sunspots: Dark spots caused by prolonged sun exposure.

    • Age Spots: Also known as liver spots, these occur because of aging or UV damage.

    • Melasma: A condition characterized by brown or dark-brown patches, often caused by hormonal changes.

    • Uneven Skin Tone: For those with generalized pigmentation irregularities, looking to achieve an even tone.


    3. Under-Eye Area (Dark Circles & Hollowing):

    • Dark Circles: PRF enhances circulation and skin health, helping to diminish the appearance of dark circles for a more refreshed look.

    • Tear Troughs: For hollow or sunken under-eye areas, PRF can restore volume, reducing the appearance of tired, gaunt eyes.

    4. Acne Scarring:

    • Scar Healing: PRF promotes tissue regeneration, improving both shallow and deep acne scars by stimulating healthy skin growth.

    • Improved Skin Texture: Over time, PRF can smooth out uneven skin texture, leaving skin clearer and more even.

    5. Hair Restoration:

    • Stimulating Hair Growth: PRF’s growth factors help revitalize hair follicles, promoting thicker, stronger hair. This is especially beneficial for those with pattern baldness or hair thinning.

    • Improving Hair Strength: In addition to stimulating new growth, PRF strengthens existing hair, reducing shedding and breakage.

    6. Neck & Décolletage Rejuvenation:

    • Wrinkle Reduction: PRF can tighten and smooth out wrinkles in delicate areas like the neck and chest.

    • Improved Skin Firmness: The collagen-boosting effects help improve elasticity, reducing sagging and creating firmer skin.

    7. Hand Rejuvenation:

    • Volume Restoration: PRF can restore lost volume in the hands, smoothing out veins and hollows that become more prominent with age.

    • Improved Skin Texture: It can also reduce age spots and sun damage, providing smoother, more even skin.

    8. Lip Enhancement & Perioral Lines:

    • Subtle Lip Enhancement: PRF helps plump and shape the lips naturally, enhancing their appearance.

    • Reducing Lip Lines: PRF can smooth out fine lines around the mouth, such as smoker's lines, by stimulating collagen production.

    9. Full-Face Skin Rejuvenation:

    • Overall Skin Health: PRF improves skin quality, texture, and radiance for a natural, refreshed appearance. It’s a great option for those looking to maintain youthful skin without invasive procedures.

    • Minimal Downtime: Since PRF uses your own blood, the risk of side effects is very low, and most people can resume normal activities the following day.


    10. Scar Treatment (Stretch Marks & Surgical Scars):

    • Scar Healing: PRF accelerates tissue regeneration, softening and reducing the appearance of scars over time.

    • Improved Texture: It can help make scars less pronounced and more even in texture.

    11. Post-Surgical or Post-Treatment Healing:

    • Accelerated Recovery: PRF helps speed up healing after surgeries or treatments, reducing swelling, bruising, and recovery time.

    • Enhanced Results: PRF can also enhance the effects of other treatments like microneedling or dermal fillers by stimulating collagen and tissue repair.


Treatment Areas

Facial

  • Full Face
  • Under-Eye
  • Lips & Perioral Lines
  • Neck & Decollete'


Other Areas

  • Hair Restoration
  • Hands
  • Scars
  • Stretch Marks

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Frequently Asked Questions

  • 1. What is PRF Treatment?

    The following steps are an example of a common approach to PRP injections: 

    For skin rejuvenation or hair loss we draw blood from a vein in the arm, then place the blood sample in a centrifuge and the centrifuge spins the blood separating its components. We then extract the platelets using a syringe and
we inject the platelets into targeted areas of the face or scalp.
The entire process may take about 1 hour and several sessions may be necessary. After receiving PRP treatment, a person can usually return to their regular activities without any limitations.

  • 2. How is PRF Different from PRP?

    PRP Therapy treatment will restore lost volume to the face, making it look plumper, erasing the appearance of lines, wrinkles and boosting the skin’s natural radiance. A small amount of blood is taken from you and is placed in a centrifuge to separate the plasma (the substance that contains all the important proteins needed to repair). The plasma will then be injected back into the desired area using very fine needles stimulating DNA repair.
The effects of PRP Therapy are vast, this is a versatile treatment that can heal scars and improve skin texture, hydrate dry, dull and lackluster skin in turn revitalising your look.

  • 3. How is PRF Treatment Performed?

    • Step 1: A small blood sample is taken.
    • Step 2: The blood is processed in a centrifuge to isolate the PRF.
    • Step 3: The PRF is applied to the treatment area via injection or topical application.

  • 4. What Areas of the Face Can PRF Treat?

    Acne is a common condition that affects people of all ages. Adults can also get acne later in life, and women reaching the age of 35 can develop breakouts because of the hormonal imbalances in their bodies. While getting pimples is not a life-threatening condition, it tends to result in loss of self-esteem and confidence. Thankfully, PRP skin treatments can help you get relief from active acne. Typically, dermatologists perform PRP using the micro-needling approach. As the healing serum works on the skin, it stimulates blood circulation, this fresh flow of blood carries away the toxins, excess sebum, and bacteria that cause the pimples. As a result, you notice clearer healthier skin a few weeks later. PRP can not only repair your skin but it can prevent the recurrence of breakouts. Acne tends to leave behind scars on the skin and the type of marks can depend on the severity of the condition. PRP for acne scars has the potential to erase the marks to a point where they are barely noticeable. That’s because the serum contains a concentration of growth factors, platelets, and other healing elements. These compounds promote the development of new collagen and elastin under the skin. As the layer plumps up, it lightens the scars significantly.

  • 5. How Long Does PRF Treatment Take?

    The property of PRP for rejuvenating collagen and elastin is also the reason why it is highly effective on signs of aging. The wrinkles, sagging skin, fine lines, and creases you see are the result of the eroding layer of collagen under the skin. Aging also thins the elastin leading to the lines you see. The PRP facial may be one of the most effective solutions because it stimulates the skin to rejuvenate itself without the use of chemicals.
Combining PRP with micro-needling accentuates the effects of the treatment. As the dermatologist runs the derma roller over the skin, it creates micro-injuries and tiny punctures and these punctures serve as a channel to help the serum reach into the lower layers of the skin so the effects start to appear sooner.

  • 6. Does PRF Treatment Hurt?

    In addition to the wrinkles, PRP works on the frown lines on your forehead and between the eyes. You can also opt for the procedure to erase the crow’s feet on the corners of your eyes. These PRP skin treatments work on the same principle as for skin regeneration. By stimulating the collagen and elastin to rejuvenate, the procedure can help smoothen the creases so the texture of your skin seems younger.

  • 7. When Will I See Results from PRF?

    Lichen Sclerosus (LS) is a skin disorder caused by your body’s immune system attacking the skin cells. This condition appears in the form of smooth or blotchy and wrinkled patches of skin. Patients may also feel pain, irritation, redness and bleeding. Typically, the symptoms appear around the genital areas in both men and women. However, some patients also see LS on the upper arms, breasts, and upper torso. Doctors explain that the use of contraceptives and lowered testosterone levels can worsen the condition.

  • 8. How Many Sessions Are Needed?

    PRP skin treatments can help you with a range of dermal conditions including hair loss and injury marks. Any kind of trauma to the skin results in uneven healing, that’s because the new tissues heal in an imperfect pattern in place of the neat, even matrix of your original tissues. PRP can reinitiate the healing process so that the new fibers are better aligned and the skin has a smoother appearance. In addition to rebuilding the collagen and elastin, PRP also creates new blood vessels in the skin for improved blood circulation and quicker healing. Talk to your dermatologist about getting PRP for your skin issues and you will be pleasantly surprised by the results.

  • 9. Is There Downtime After PRF Treatment?

    PRP Threapy can also be used to stimulate hair follicles encouraging regrowth to thinning and lost hair. Our staff at Asteria Aesthetics are highly skilled and experienced in the practice of PRP Therapy, which is particularly important as the treatment consists of multiple injections into the affected area and a skilled application technique will impact the overall success, particularly when using PRP to treat hair loss.

  • 10. Are There Any Risks or Side Effects?

    Since PRF uses your own blood, the risk of allergic reactions is extremely low. Minor

    risks include temporary swelling, bruising, or irritation at the injection sites. These

    effects are typically short-lived.

  • 11. Who is a Good Candidate for PRF?

    PRF is ideal for individuals looking for a natural, non-surgical method to improve skin

    quality, reduce signs of aging, or restore hair volume. It’s especially beneficial for

    those with mild to moderate signs of aging or acne scars.

  • 12. How Long Do Results Last?

    Results typically last 6–12 months, depending on individual factors like age, skin

    condition, and the area treated. Maintenance treatments are recommended to

    preserve results.

  • 13. Can PRF Be Combined with Other Treatments?

    Yes, PRF can be combined with treatments like microneedling, dermal fillers, Botox,

    and laser treatments to enhance overall results.

  • 14. Is PRF Safe?

    PRF is a safe, minimally invasive procedure with little risk of side effects, as it uses

    your own blood. It’s well-tolerated by most people and requires minimal recovery

    time.